ABSTRACT Objective: To evaluate the efficacy and complications of oral and intravenous fluid therapy in newborns with hypernatremic dehydration. Methods: A total of 75 term and near term (>35 weeks) neonates with hypernatremic dehydration (Na≥150 mmol/L) were included in this retrospective-study. The patients were divided into two groups according to therapy approach for rehydration (breast [...]
What is the safe approach for neonatal hypernatremic dehydration?: a retrospective study from a neonatal intensive care unit.
OBJECTIVES: The aims of this study were to evaluate the prevalence, complications, and mortality of hypernatremic dehydration in neonates and to compare the effect of correction rate at 48 hours on mortality and on neurological outcome in the short term. METHODS: This retrospective study was conducted between January 2007 and 2011 in the neonatal intensive [...]
Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. Michael L. Moritz, MD, is an associate professor of pediatrics at the University of Pittsburgh School of Medicine and the clinical director of pediatric nephrology and medical director of pediatric dialysis at the Children's Hospital of Pittsburgh of [...]
Background/objectives:In sedentary adults, hydration is mostly influenced by total fluid intake and not by sweat losses; moreover, low daily fluid intake is associated with adverse health outcomes. This study aimed to model the relation between total fluid intake and urinary hydration biomarkers.Subjects/methods:During 4 consecutive weekdays, 82 adults (age, 31.6±4.3 years; body mass index, 23.2±2.7 kg/m2; 52% [...]
Effect of varying the concentrations of carbohydrate and milk protein in rehydration solutions ingested after exercise in the heat.
The present study investigated the relationship between the milk protein content of a rehydration solution and fluid balance after exercise-induced dehydration. On three occasions, eight healthy males were dehydrated to an identical degree of body mass loss (BML, approximately 1•8 %) by intermittent cycling in the heat, rehydrating with 150 % of their BML over [...]
PURPOSE: This work combines and reanalyzes 5 yr of exercise-associated hyponatremia (EAH) research at 161-km ultramarathons in northern California with primary purposes to define the relationship between postrace blood sodium concentration ([Na]) and change in body weight; to examine the interactions among EAH incidence, ambient temperature, and hydration state; and to explore the effect of [...]
The acute effects of fluid intake on urine specific gravity and fluid retention in a mildly dehydrated state.
Logan-Sprenger, HM and Spriet, LL. The acute effects of fluid intake on urine specific gravity and fluid retention in a mildly dehydrated state. J Strength Cond Res 27(4): 1002-1008, 2013-Many athletes arrive at training sessions and competitions in a mildly hypohydrated (HYPO) state and are instructed to drink fluids before exercise to reach a euhydrated [...]
OBJECTIVE: This study explored whether the increased extracellular relative to intracellular fluid (ECF/ICF) ratio in obesity mightreflect osmotic effects of elevated plasma solute concentrations. DESIGN: Cross-sectional, epidemiological survey. SETTING AND SUBJECTS: The present analysis used nationally representative data from the Third National Health and Nutrition Examination Survey on community-dwelling adults (aged 40-59 years) in the [...]
Indices ofÂ plasmaÂ hypertonicity, elevatedÂ plasmaÂ concentrations of solutes that draw fluid out of cells by osmosis, are needed to pursueÂ hypertonicityÂ as a possible risk factor for obesity and chronic disease. This paper proposes a new index that may be more sensitive to mildÂ hypertonicityÂ inÂ vivoÂ at a point in time than traditional measures. The index compares mean corpuscular volume (MCV) estimates from [...]
PURPOSE OF REVIEW: The purpose of this review is to update the knowledge onÂ diarrhoea, a common problem inÂ critically illÂ patients. Epidemiological data will be discussed, with special emphasis onÂ diarrhoeaÂ in tube-fed patients and during antibiotic therapy. The possible preventive and therapeutic measures will be presented. RECENT FINDINGS: The need for concise definitions ofÂ diarrhoeaÂ was recently re-emphasized. The use [...]