ABSTRACT Objective: To evaluate the efficacy and complications of oral and intravenous fluid therapy in newborns with hypernatremic dehydration. Methods: A total of 75 term and near term (>35 weeks) neonates with hypernatremic dehydration (Na≥150 mmol/L) were included in this retrospective-study. The patients were divided into two groups according to therapy approach for rehydration (breast [...]
What is the safe approach for neonatal hypernatremic dehydration?: a retrospective study from a neonatal intensive care unit.
OBJECTIVES: The aims of this study were to evaluate the prevalence, complications, and mortality of hypernatremic dehydration in neonates and to compare the effect of correction rate at 48 hours on mortality and on neurological outcome in the short term. METHODS: This retrospective study was conducted between January 2007 and 2011 in the neonatal intensive [...]
Water is essential for health and vital for all bodily functions. If water losses are not replaced then dehydration can occur and even mild dehydration is associated with negative effects on health including impaired cognitive function. Studies in schoolchildren have found that many are arriving at school with a hydration deficit and, once they arrive, [...]
Cost-effectiveness of recombinant human hyaluronidase-facilitated subcutaneous versus intravenous rehydration in children with mild to moderate dehydration.
OBJECTIVE: To evaluate the cost-effectiveness of recombinant human hyaluronidase-facilitated subcutaneous (rHFSC) fluid administration compared to intravenous (IV) fluid administration in children with mild to moderate dehydration in the emergency department (ED). METHODS: A decision analytic model was created based on the results of a controlled clinical trial that compared the administration of isotonic fluids via [...]
The effect of beverages varying in glycaemic load on postprandial glucose responses, appetite and cognition in 10-12-year-old school children.
Reducing glycaemic index (GI) and glycaemic load (GL) inconsistently improves aspects of cognitive function and appetite in children. Whether altering the GL by lowering carbohydrate relative to protein and fat has a role in these effects is unknown. Therefore, we assessed the differential effects of beverages varying in GL and dairy composition on appetite, energy [...]
Comparison of Ringers Lactate vs Normal Saline in Children with Acute Diarrhea and Severe Dehydration: A Double Blind Randomized Controlled Trial.
OBJECTIVE: WHO recommends Ringers lactate (RL) and Normal Saline (NS) for rapid intravenous rehydration in childhood diarrhea and severe dehydration. We compared these two fluids for improvement in pH over baseline during rapid intravenous rehydration in children with acute diarrhea. DESIGN: Double-blind randomized controlled trial. SETTING: Pediatric emergency facilities at a tertiary-care referral hospital. INTERVENTION: [...]
Hyponatremia associated with diarrhea is usually caused by dehydration, with salt loss accompanying the excessive loss of water. On the other hand, hyponatremia in this setting can occasionally be caused by excess ingestion or administration of hypotonic fluids (1, 2). In this report, we describe the differential diagnosis of hyponatremia in an infant.
BACKGROUND: Most acute wheezing episodes in preschool children are associated with rhinovirus. Rhinovirus decreases extracellular adenosine triphosphate levels, leading to airway surface liquid dehydration. This, along with submucosal edema, mucus plaques, and inflammation, causes failure of mucus clearance. These preschool children do not respond well to available treatments, even oral steroids. This calls for pro-mucus [...]
The effect of a meal and water loading on heart rate variability in children with functional dyspepsia
BACKGROUND: Alteration in autonomic function has been implicated as a possible pathophysiologic mechanism in functional dyspepsia (FD) in adults.nnMETHODS: This was a two-part study. For the first part of the study, nine children with FD and 28 controls underwent heart rate variability (HRV) analysis for 30 min baseline and for 60 min following a test [...]