ENDOCRINE AND RENAL RESPONSE TO WATER LOADING AND WATER RESTRICTION IN NORMAL MAN

1. Nine normal subjects (eight male, one female) on a fixed daily intake of 150 mmol of sodium and 80 mmol of potassium, were randomized to receive either 3 days of 1.0 litre total water intake/24 h (food + fluid) or 4 days of 6.8 litres total water intake/24 h, and were then crossed over [...]

RENAL MANAGEMENT OF SODIUM UNDER INDOMETHACIN AND ALDOSTERONE IN THE ELDERLY

The tubular handling of sodium in two groups of healthy old people, under the action of indomethacin and aldosterone was studied. Urinary aldosterone elimination was measured. From the results obtained, it is deduced that the elderly lose sodium through incompetence of the distal nephron. The possibility is put forward of a Na-K-ATPase deficit and/or interstitial [...]

By |2013-01-31T18:34:05+00:00enero 31st, 2013|Age and the elderly, Scientific papers|0 Comments

INGESTION OF COLD FLUIDS: RELATED TO ONSET OF ARRHYTHMIAS?

Although the results of this study provide too limited a database for establishing definitive guidelines for practice, they underscore the need for critical care nurses to focus observations on patients' responses to iced fluid restriction. It is important to determine whether and to what extent limiting ingestion of iced fluids induces patient stress, a factor [...]

EFFECT OF SALT INTAKE ON RENAL EXCRETION OF WATER IN HUMANS

Two studies were performed to determine the quantitative relationship between salt intake and urinary volume (U(v)) in humans. In study 1, 104 untreated hypertensives were studied on the fifth day of a high- and a low-salt diet. The 24-hour U(v) was 2.2 L (urinary sodium [U(Na)] 277 mmol) on the high-salt diet and decreased to [...]

EFFECTS OF FLUID, ELECTROLYTE AND SUBSTRATE INGESTION ON ENDURANCE CAPACITY

The availability of carbohydrate (CHO) as a substrate for the exercising muscles is known to be a limiting factor in the performance of prolonged cycle exercise, and provision of exogenous CHO in the form of glucose can increase endurance capacity. The present study examined the effects of ingestion of fluids and of CHO in different [...]

HYPERNATREMIA IN ELDERLY PATIENTS. A HETEROGENEOUS, MORBID, AND IATROGENIC ENTITY

The causes, therapy for, and consequences of hypernatremia in elderly patients are not well understood. We found that in 15,187 consecutive hospital admissions, 162 (1.1%) patients who were at least 60 years of age had serum sodium levels that measured greater than 148 meq/L. Of that 162, 57% had become hypernatremic in the hospital; the [...]

By |2013-01-31T18:33:42+00:00enero 31st, 2013|Age and the elderly, Scientific papers|0 Comments