AMPK AGONISTS AMELIORATE SODIUM AND FLUID TRANSPORT AND INFLAMMATION IN CYSTIC FIBROSIS AIRWAY EPITHELIAL CELLS

The metabolic sensor AMP-activated kinase (AMPK) inhibits both the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) Cl(-) channel and epithelial Na(+) channel (ENaC), and may inhibit secretion of proinflammatory cytokines in epithelia. Here we have tested in primary polarized CF and non-CF human bronchial epithelial (HBE) cells the effects of AMPK activators, metformin and 5-aminoimidazole-4-carboxamide-1-beta-D-riboside [...]

By |2017-05-21T03:21:06+00:00enero 31st, 2013|Cystic fibrosis, Documentos científicos|Comentarios desactivados en AMPK AGONISTS AMELIORATE SODIUM AND FLUID TRANSPORT AND INFLAMMATION IN CYSTIC FIBROSIS AIRWAY EPITHELIAL CELLS

Thirst in the elderly with and without heart failure.

Elderly patients with heart failure (HF) may be troubled by thirst, despite the fact that elderly have an impaired ability to sense thirst. The present study was undertaken to compare the intensity of thirst in patients with and without HF and to evaluate how this symptom relates to the health-related quality of life and indices [...]

By |2017-05-21T03:21:27+00:00enero 31st, 2013|Assessment methodologies, Documentos científicos|Comentarios desactivados en Thirst in the elderly with and without heart failure.

PHYSICAL ACTIVITY, FOOD INTAKE, AND BODY WEIGHT REGULATION: INSIGHTS FROM DOUBLY LABELED WATER STUDIES

Body weight and energy balance can be maintained by adapting energy intake to changes in energy expenditure and vice versa, whereas short-term changes in energy expenditure are mainly caused by physical activity. This review investigates whether physical activity is affected by over- and undereating, whether intake is affected by an increase or a decrease in [...]

By |2017-05-21T03:21:26+00:00enero 31st, 2013|Documentos científicos, Exercise and sport|Comentarios desactivados en PHYSICAL ACTIVITY, FOOD INTAKE, AND BODY WEIGHT REGULATION: INSIGHTS FROM DOUBLY LABELED WATER STUDIES

HYDRATION, HYDRATION, HYDRATION

Throughout the world, large numbers of manual workers perform physically demanding labour in conditions of high environmental heat stress. Although the importance of adequate hydration in combating heat stress is universally recognized, studies in a range of worker groups have demonstrated a disturbingly poor hydration level in a high proportion of at-risk workers. Management of [...]

By |2017-05-21T03:21:26+00:00enero 31st, 2013|Documentos científicos, Hydration and health|Comentarios desactivados en HYDRATION, HYDRATION, HYDRATION

Fluid replacement and glucose infusion during exercise prevent cardiovascular drift.

This study examined the influence of both hydration and blood glucose concentration on cardiovascular drift during exercise. We first determined if the prevention of dehydration during exercise by full fluid replacement prevents the decline in stroke volume (SV) and cardiac output (CO) during prolonged exercise. On two occasions, 10 endurance-trained subjects cycled an ergometer in [...]

By |2017-05-21T03:21:27+00:00enero 31st, 2013|Assessment methodologies, Documentos científicos|Comentarios desactivados en Fluid replacement and glucose infusion during exercise prevent cardiovascular drift.

EFFECTS OF ROOIBOS TEA, BOTTLED WATER, AND A CARBOHYDRATE BEVERAGE ON BLOOD AND URINARY MEASURES OF HYDRATION AFTER ACUTE DEHYDRATION

Rooibos tea contains polyphenol antioxidants, including flavonoids and phenolic acids that are potent free radical scavengers and has purported benefits for accelerated rehydration. The objective was to evaluate the effects of three different drinks (rooibos tea, bottled water, and a carbohydrate beverage) on blood and urinary markers of hydration after acute dehydration in collegiate wrestlers. [...]

By |2017-05-21T03:21:26+00:00enero 31st, 2013|Body water content; body composition, Documentos científicos|Comentarios desactivados en EFFECTS OF ROOIBOS TEA, BOTTLED WATER, AND A CARBOHYDRATE BEVERAGE ON BLOOD AND URINARY MEASURES OF HYDRATION AFTER ACUTE DEHYDRATION

HYDRATION STATUS AND THE DIURETIC ACTION OF A SMALL DOSE OF ALCOHOL

Aim: This study was conducted to examine the effect of consuming a dilute alcohol solution (weak beer) on urine production in euhydrated and hypohydrated individuals. Methods: Twelve males completed an intermittent cycle protocol in hot (35.1 +/- 0.3 degrees C), humid (68 +/- 2%) conditions to dehydrate by 1.9 +/- 0.3% body mass in the [...]

By |2017-05-21T03:21:27+00:00enero 31st, 2013|Caffeine and other diuretics, Documentos científicos|Comentarios desactivados en HYDRATION STATUS AND THE DIURETIC ACTION OF A SMALL DOSE OF ALCOHOL

Dietary reference intakes for water, sodium, potassium, chloride and sulphate.

This report is one in a series that presents a comprehensive set of reference values for nutrient intakes for healthy U.S. and Canadian individuals and populations. It is a product of the Food and Nutrition Board (FNB) of the Institute of Medicine, working in cooperation with Canadian scientists. The report establishes a set of reference [...]

By |2017-05-21T03:21:06+00:00enero 31st, 2013|Cardiovascular disease, cardiovascular function, Documentos científicos|Comentarios desactivados en Dietary reference intakes for water, sodium, potassium, chloride and sulphate.