OLYCYTHEMIA AND HYDRATION: EFFECTS ON THERMOREGULATION AND BLOOD VOLUME DURING EXERCISE-HEAT STRESS

We studied the effects of autologous erythrocyte infusion on thermoregulation and blood volume during exercise in the heat. Specifically, we wanted to determine whether heat-acclimated subjects, as well as hypohydrated subjects, would have a thermoregulatory advantage from acute polycythemia during exercise in the heat. Five heat-acclimated males attempted four heat stress tests (HSTs): two pre- [...]

By |2013-01-31T18:34:19+00:00enero 31st, 2013|Cardiovascular disease, cardiovascular function, Scientific papers|0 Comments
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CONTROL OF THERMOREGULATORY SWEATING DURING EXERCISE IN THE HEAT

The purposes of this study were the following: 1) to determine whether erythrocyte infusion alters the control of thermoregulatory sweating and 2) to demonstrate how increases and decreases of both plasma tonicity and blood volume influence the thermoregulatory control parameters of threshold temperature and sweating sensitivity. Six non-heat-acclimated and five heat-acclimated males attempted heat stress [...]

By |2013-01-31T18:34:19+00:00enero 31st, 2013|Exercise and sport, Scientific papers|0 Comments
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PLASMA OSMOLALITY AND URINARY CONCENTRATION AND DILUTION DURING AND AFTER PREGNANCY: EVIDENCE THAT LATERAL RECUMBENCY INHIBITS MAXIMAL URINARY CONCENTRATING ABILITY.

In nine women studied serially before conception and through the first trimester, plasma osmolality (Posm) started to decline with the first missed menstrual period, was significantly decreased by the fifth week of pregnancy and was 10 mosmol/kg lower than preconception values by the tenth week, changing little thereafter. Changes in plasma sodium (and its attendant [...]

By |2013-01-31T18:34:19+00:00enero 31st, 2013|Pregnancy and infancy, Scientific papers|0 Comments
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HUMAN INTRAVASCULAR IMMUNOGLOBULIN RESPONSES TO EXERCISE-HEAT AND HYPOHYDRATION

Several investigators have suggested that prolonged exercise and hypohydration alter the intravascular mass of immunoglobulins. Those studies, however, have methodological concerns which make generalizations from their data very tenuous. This study examined the effects of prolonged moderate intensity exercise in the heat and hypohydration on changes in the intravascular mass of immunoglobulins. Five heat-acclimated males [...]

By |2013-01-31T18:34:19+00:00enero 31st, 2013|Hydration status: effects on physiology and metabolism, Scientific papers|0 Comments
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CHANGES IN THE METABOLIC CLEARANCE OF VASOPRESSIN AND IN PLASMA VASOPRESSINASE THROUGHOUT HUMAN PREGNANCY.

Metabolic clearance rates (MCR) of arginine vasopressin (AVP) were measured serially in five women starting before conception, during gestational weeks 7-8 (early), 22-24 (middle), and 36-38 (late pregnancy), and again 10-12 wk postpartum. Hormonal disposal rates were determined after water loading to suppress endogenous AVP release using a constant infusion method designed to achieve three [...]

By |2013-01-31T18:34:19+00:00enero 31st, 2013|Hydration status: effects on physiology and metabolism, Scientific papers|0 Comments
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METABOLIC CLEARANCE OF VASOPRESSIN AND AN ANALOGUE RESISTANT TO VASOPRESSINASE IN HUMAN PREGNANCY

The metabolic clearance rate (MCR) of arginine vasopressin (AVP) increases fourfold during human pregnancy. To explore whether circulating vasopressinase may play a role in this change, six women underwent a three-tier infusion clearance study, twice, in random order, to determine the MCRs of either AVP or 1-deamino-8-D-AVP (dDAVP, an analogue resistant to degradation by vasopressinase). [...]

By |2013-01-31T18:34:19+00:00enero 31st, 2013|Pregnancy and infancy, Scientific papers|0 Comments
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ALTERED OSMOTIC THRESHOLDS FOR VASOPRESSIN SECRETION AND THIRST IN HUMAN PREGNANCY

Osmoregulation was studied in eight women during late pregnancy and again 8-10 wk postpartum. Base-line plasma osmolality (Posmol) was significantly lower during (280.9 +/- 2.1 mosmol/kg, SD) than after (289.4 +/- 2.1 mosmol/kg) pregnancy yet 24-h urinary volume and plasma arginine vasopressin (PAVP) measured in vasopressinase-inactivated blood was similar in both groups (pregnancy, 1.39 +/- [...]

By |2013-01-31T18:34:19+00:00enero 31st, 2013|Pregnancy and infancy, Scientific papers|0 Comments
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