Brain apparent diffusion coefficient decrease during correction of severe hypernatremic dehydration

We report on the brain diffusion MR imaging findings in a neonate with severe hypernatremic dehydration, which resulted in cerebral edema (osmotic edema) and in apparent diffusion coefficient decrease, despite a careful and slow rehydration. This report provides in vivo insight into nervous cell response to osmotic challenge. PMID: 16091515 [PubMed – indexed for MEDLINE