THE RESPONSE OF ARGININE VASOPRESSIN TO INTRAVENOUS ETHANOL AND HYPERTONIC SALINE IN MAN: THE IMPACT OF AGING

The effect of age on the hypothalamic-hypophyseal-renal axis in normal man was determined by assaying plasma arginine vasopressin (AVP) responses to inhibitory and to secretory stimuli. Nine young (21-49 years) and 13 old (54-92 years) subjects received IV ethanol (375 mg/m2 per min). AVP levels fell progressively during the infusion in the young group, but [...]

By |2013-01-31T18:34:05+00:00enero 31st, 2013|Age and the elderly, Scientific papers|0 Comments

AGE AND HYPOHYDRATION INDEPENDENTLY INFLUENCE THE PERIPHERAL VASCULAR RESPONSE TO HEAT STRESS

Seven young (Y, 22-28 yr) and seven middle-aged (MA, 49-60 yr) normotensive men of similar body size, fatness, and maximal oxygen uptake (VO2max) were exposed to a heat challenge in an environmental chamber (48 degrees C, 15% relative humidity). Tests were performed in two hydration states: hydrated (H, 25 ml water/kg body wt 1 h [...]

By |2013-01-31T18:34:05+00:00enero 31st, 2013|Age and the elderly, Scientific papers|0 Comments

RENAL MANAGEMENT OF SODIUM UNDER INDOMETHACIN AND ALDOSTERONE IN THE ELDERLY

The tubular handling of sodium in two groups of healthy old people, under the action of indomethacin and aldosterone was studied. Urinary aldosterone elimination was measured. From the results obtained, it is deduced that the elderly lose sodium through incompetence of the distal nephron. The possibility is put forward of a Na-K-ATPase deficit and/or interstitial [...]

By |2013-01-31T18:34:05+00:00enero 31st, 2013|Age and the elderly, Scientific papers|0 Comments

BODY FLUID BALANCE IN DEHYDRATED HEALTHY OLDER MEN: THIRST AND RENAL OSMOREGULATION

We examined osmotic control of thirst and free water clearance in healthy older (65+, n = 10) and younger (Y, n = 6) subjects during a 3-h rehydration period after an approximately 2.4% decrease in body weight. Plasma volume (PV), plasma osmolality (Posm), renal function, and thirst were measured before and after dehydration and during [...]

By |2013-01-31T18:34:05+00:00enero 31st, 2013|Age and the elderly, Scientific papers|0 Comments

EFFECTS OF HYPERTONICITY ON WATER INTAKE IN THE ELDERLY: AN AGE-RELATED FAILURE

Dehydration is a common clinical syndrome associated with many illnesses and treatments in the elderly. Prior studies have shown diminished sensation of thirst during water deprivation. It is currently unclear whether age-related decreases in thirst perception impair the defense against a hyperosmolar challenge. To examine the impact of water ingestion during hyperosmolality, young and old [...]

By |2013-01-31T18:34:05+00:00enero 31st, 2013|Age and the elderly, Scientific papers|0 Comments

CROSS-SECTIONAL AGE DIFFERENCES IN BODY COMPOSITION IN PERSONS 60+ YEARS OF AGE

BACKGROUND. There is little information for age differences in body composition in elderly people > 65 years of age, especially for those > 80 years. As the proportion of people older than 65 years is expected to nearly double during the next few decades, this information is needed. METHODS. Age differences in body composition and [...]

By |2013-01-31T18:34:05+00:00enero 31st, 2013|Age and the elderly, Scientific papers|0 Comments