BACKGROUND: The water-deficit equation {WD(1) = 0.6 — B(m) — [1 - (140 · Na(+))]; B(m) denotes body mass} is used in medicine and nutrition to estimate the volume (L) of water required to correct dehydration during the initial stages of fluid-replacement therapy. Several equation assumptions may limit its accuracy, but none have been systematically [...]
Objective: Assessment of fluid status in chronic peritoneal dialysis (PD) patients is complex. Clinical evaluation based solely on body weight, blood pressure, volume of ultrafiltration (UF) and peripheral edema is insufficient. A non-invasive test, bioelectrical impedance analysis (BIA) might be of potential benefit. Aim: To test whether BIA correlates with other ancillary markers of extracellular [...]
Fluid management is recognized as a basic component of management of patients on dialysis. Fluid overload is an important adverse factor in patient outcomes, and the negative effects of fluid depletion, including on residual renal function, are aIso increasingly being recognized. The complexities of fluid distribution in renal failure need to be understood to inform [...]
BACKGROUND AND OBJECTIVE. The level of dehydration has been known to be a predisposing factor for the development of decompression sickness in divers. The aim of this study was to determine the level of dehydration in divers who dove with heliox and to determine whether the source of this dehydration was intracellular and/or extracellular by [...]
Background: Patients admitted to surgery may be dehydrated, which is difficult to diagnose except when it is severe (>5% of the body weight). We hypothesized that modest dehydration can be detected by kinetic analysis of the blood hemoglobin concentration after a bolus infusion of crystalloid fluid.Methods:Four series of experiments were performed on 10 conscious, healthy [...]
OBJECTIVE: To investigate whether unstimulated whole saliva flow rate (UFR) and osmolality (Sosm) track changes in hydration status during 48h of restricted fluid intake (RF) or combined fluid and energy restriction (RF+RE). Following the 48h periods, UFR and Sosm were assessed after acute exercise dehydration and rehydration. DESIGN: Thirteen healthy males completed three trials in a randomised order: control (CON) where participants received their estimated energy (12,154+/-230kJ/d: mean+/-S.E.M) and fluid (3912+/-140ml/d) [...]
PURPOSE: Firstly, to identify whether saliva flow rate, osmolality, and total protein are potential markers of hydration, we compared changes in these parameters with changes in plasma osmolality during progressive dehydration. Secondly, we compared the sensitivity of saliva parameters to track hydration changes with the sensitivity of urine osmolality. Thirdly, to test the hypothesis thatdehydration, rather than neuroendocrine regulation, is responsible for the decrease in saliva flow rate during prolonged [...]
We investigated whether an athlete's self-chosen nutrition strategy (A), compared with a scientifically determined one (S), led to an improved endurance performance in a laboratory time trial after an endurance exercise. S consisted of about 1000 mL·h(-1) fluid, in portions of 250 mL every 15 min, 0.5 g sodium·L(-1), 60 g glucose·h(-1), 30 g fructose·h(-1), and 5 mg caffeine·kg body mass(-1). Eighteen [...]
The cardiovascular response to standing (sit-to-stand change in heart rate; SSΔHR) is commonly employed as a screening tool to detect hypohydration (body water deficit). No study has systematically evaluated SSΔHR cut points using different magnitudes or different types of controlled hypohydration. The objective of this study was to determine the diagnostic accuracy of the often [...]
The quantitative and qualitative estimation of total body fluid content has proven to be crucial for both diagnosis and prognosis assessment in patients with heart failure. The aim of this review is to summarize the current techniques for assessing body hydration status as well as the principal biomarkers associated with acute heart failure (AHF). Although [...]