The purpose of this study was to determine the thermal and circulatory responses of seven runners (X VO2max = 66 ml kg min) to two bouts of high intensity prolonged treadmill running (PTR) [each 80-min at 70% VO2max] spaced by a 90-min rest. After the transition to exercise, oxygen uptake (VO2) and percent change in [...]
No abstract available.
The renal and vasopressin (AVP) response to a standard oral water load (20 ml/kg) was examined in a group of water-replete healthy elderly men (n = 6). Two groups, respectively, of water-replete and water-deprived young healthy volunteers acted as controls. After 2 h, the old group had excreted 41 +/- 2.4% (mean +/- SEM) of [...]
This study investigated the individual and combined effects of water and carbohydrate ingestion during prolonged cycling on maximal neuromuscular power (P(max)), thermoregulation, cardiovascular function, and metabolism. Eight endurance-trained cyclists exercised for 122 min at 62% maximal oxygen uptake in a 35 degrees C environment (50% relative humidity, 2 m/s fan speed). P(max) was measured in [...]
OBJECTIVE: To determine whether rates of intestinal fluid absorption and renal diuresis can match high rates of fluid ingestion in healthy humans exposed to oral fluid overload, thereby preventing the development of hyponatraemia either by reverse sodium movement across the intestine (the Priestley-Haldane effect) or by expansion of the extracellular fluid volume. METHODS: Changes in [...]
The mechanisms of renal tubular dysfunction in old age have been examined in twenty-eight clinically healthy elderly subjects without infection, and in fourteen subjects of similar age with laboratory evidence of intrarenal infection. The data were compared with those from thirteen clinically healthy young subjects. Studied were: proximal tubular (Tm(PAH)) and distal tubular (CH2O) activity, [...]
No abstract available.
Dehydration amounting to about 10% of body weight was induced in adult male rats by exposure to a hot, dry environment (D.B.T., 36 degrees C; R.H., 20%) over 6 to 8 hr. The volumes of total water (TW), extracellular fluid (ECF), and plasma (PV) were determined both on individual tissues and on the whole body [...]
No abstract available.
No abstract available.