During the bed-rest in the young subjects, the water intake should be depressed, because the diuretic is probably accelerated, and then the total body water and body weight is decreased by the water loss. In our previous study in 1991, we have reported that urinary volume was gradually increased, while water intake was decreased. Therefore, it was concluded that the decrease in the water intake and the increase in the urinary volume should bring to the negative water balance. In the present study, it is studied whether urinary volume is independent on water intake during 20 days horizontal bed-rest in young woman. PMID: 11538508 [PubMed – indexed for MEDLINE]