AMPK AGONISTS AMELIORATE SODIUM AND FLUID TRANSPORT AND INFLAMMATION IN CYSTIC FIBROSIS AIRWAY EPITHELIAL CELLS

The metabolic sensor AMP-activated kinase (AMPK) inhibits both the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) Cl(-) channel and epithelial Na(+) channel (ENaC), and may inhibit secretion of proinflammatory cytokines in epithelia. Here we have tested in primary polarized CF and non-CF human bronchial epithelial (HBE) cells the effects of AMPK activators, metformin and 5-aminoimidazole-4-carboxamide-1-beta-D-riboside [...]

By |2017-05-21T03:21:06+00:00enero 31st, 2013|Cystic fibrosis, Documentos científicos|Comentarios desactivados en AMPK AGONISTS AMELIORATE SODIUM AND FLUID TRANSPORT AND INFLAMMATION IN CYSTIC FIBROSIS AIRWAY EPITHELIAL CELLS

American College of Sports Medicine position stand. Exercise and fluidreplacement.

This Position Stand provides guidance on fluid replacement to sustain appropriate hydration of individuals performing physical activity. The goal of prehydrating is to start the activity euhydrated and with normal plasma electrolyte levels. Prehydrating with beverages, in addition to normal meals and fluid intake, should be initiated when needed at least several hours before the [...]

By |2017-05-21T03:21:28+00:00enero 31st, 2013|Documentos científicos, Exercise and sport|Comentarios desactivados en American College of Sports Medicine position stand. Exercise and fluidreplacement.

Dietary reference intakes for water, sodium, potassium, chloride and sulphate.

This report is one in a series that presents a comprehensive set of reference values for nutrient intakes for healthy U.S. and Canadian individuals and populations. It is a product of the Food and Nutrition Board (FNB) of the Institute of Medicine, working in cooperation with Canadian scientists. The report establishes a set of reference [...]

By |2017-05-21T03:21:06+00:00enero 31st, 2013|Cardiovascular disease, cardiovascular function, Documentos científicos|Comentarios desactivados en Dietary reference intakes for water, sodium, potassium, chloride and sulphate.

A META-ANALYSIS OF OUTCOMES OF HYDRATION INTERVENTION ON PHONATION THRESHOLD PRESSURE

OBJECTIVES: Vocal fold hydration is purported to promote optimal biomechanical characteristics of vocal fold mucosa, increase efficiency of vocal fold oscillation, and enhance voice quality. The purpose of this work was to determine the magnitude and consistency of the effect of vocal fold hydration on vocal fold function across published clinical studies. METHODS: We completed [...]

By |2017-05-21T03:21:28+00:00enero 31st, 2013|Body water content; body composition, Documentos científicos|Comentarios desactivados en A META-ANALYSIS OF OUTCOMES OF HYDRATION INTERVENTION ON PHONATION THRESHOLD PRESSURE

INHALED MANNITOL IMPROVES THE HYDRATION AND SURFACE PROPERTIES OF SPUTUM IN PATIENTS WITH CYSTIC FIBROSIS

The airway mucus in patients with cystic fibrosis (CF) is dehydrated and adhesive and accumulates in the airways, resulting in chronic inflammation, infection, and progressive loss of lung function. Inhaled mannitol improves mucus clearance and, when administered over 2 weeks, it improves lung function in CF (Jaques et al. Chest. 2008;133(6):1388-1396). The changes in the [...]

By |2017-05-21T03:21:25+00:00enero 31st, 2013|Cystic fibrosis, Documentos científicos|Comentarios desactivados en INHALED MANNITOL IMPROVES THE HYDRATION AND SURFACE PROPERTIES OF SPUTUM IN PATIENTS WITH CYSTIC FIBROSIS

Effect of beverage osmolality on intestinal fluid absorption during exercise.

To determine how osmolality of an orally ingested fluid-replacement beverage would alter intestinal fluid absorption from the duodenum and/or jejunum during 85 min of cycle exercise (63.3 +/- 0.9% peak O2 uptake) in a cool environment (22 degreesC), seven subjects (5 men, 2 women, peak O2 uptake = 54.5 +/- 3.8 ml . kg-1 . [...]

By |2017-05-21T03:21:06+00:00enero 31st, 2013|Documentos científicos, Exercise and sport|Comentarios desactivados en Effect of beverage osmolality on intestinal fluid absorption during exercise.

A SYSTEMATIC DATA REVIEW OF THE COST OF REHYDRATION THERAPY

Dehydration secondary to acute gastroenteritis is a commonly encountered condition among patients presenting to physicians' offices and hospital EDs. Treatment options consist of oral rehydration therapy (ORT), intravenous rehydration therapy (IVRT) and subcutaneous rehydration therapy (SCRT). Although most patients with dehydration can be effectively treated in an outpatient setting, hospitalization is frequently warranted, with estimated [...]

By |2017-05-21T03:21:28+00:00enero 31st, 2013|Documentos científicos, Gastrointestinal health and function; oral rehydration therapy|Comentarios desactivados en A SYSTEMATIC DATA REVIEW OF THE COST OF REHYDRATION THERAPY

Effect of fluid ingestion on muscle metabolism during prolonged exercise.

Five trained men were studied during 2 h of cycling exercise at 67% peak oxygen uptake at 20-22 degrees C to examine the effect of fluid ingestion on muscle metabolism. On one occasion, the subjects completed this exercise without fluid ingestion(NF) while on the other they ingested a volume of distilled deionized water that prevented [...]

By |2017-05-21T03:21:07+00:00enero 31st, 2013|Assessment methodologies, Documentos científicos|Comentarios desactivados en Effect of fluid ingestion on muscle metabolism during prolonged exercise.

THERMOREGULATORY RESPONSES AND HYDRATION PRACTICES IN HEAT-ACCLIMATIZED ADOLESCENTS DURING PRESEASON HIGH SCHOOL FOOTBALL

Previous researchers have not investigated the thermoregulatory responses to multiple consecutive days of American football in adolescents. OBJECTIVE: To examine the thermoregulatory and hydration responses of high school players during formal preseason football practices. DESIGN: Observational study. SETTING: Players practiced outdoors in late August once per day on days 1 through 5, twice per day [...]

By |2017-05-21T03:21:26+00:00enero 31st, 2013|Children, Documentos científicos|Comentarios desactivados en THERMOREGULATORY RESPONSES AND HYDRATION PRACTICES IN HEAT-ACCLIMATIZED ADOLESCENTS DURING PRESEASON HIGH SCHOOL FOOTBALL

PHYSICAL ACTIVITY, FOOD INTAKE, AND BODY WEIGHT REGULATION: INSIGHTS FROM DOUBLY LABELED WATER STUDIES

Body weight and energy balance can be maintained by adapting energy intake to changes in energy expenditure and vice versa, whereas short-term changes in energy expenditure are mainly caused by physical activity. This review investigates whether physical activity is affected by over- and undereating, whether intake is affected by an increase or a decrease in [...]

By |2017-05-21T03:21:26+00:00enero 31st, 2013|Documentos científicos, Exercise and sport|Comentarios desactivados en PHYSICAL ACTIVITY, FOOD INTAKE, AND BODY WEIGHT REGULATION: INSIGHTS FROM DOUBLY LABELED WATER STUDIES