DILUTION AND REDISTRIBUTION EFFECTS OF RAPID 2-LITRE INFUSIONS OF 0.9% (W/V) SALINE AND 5% (W/V) DEXTROSE ON HAEMATOLOGICAL PARAMETERS AND SERUM BIOCHEMISTRY IN NORMAL SUBJECTS: A DOUBLE-BLIND CROSSOVER STUDY
Although hypoalbuminaemia after injury may result from increased vascular permeability, dilution secondary to crystalloid infusions may contribute significantly. In this double-blind crossover study, the effects of bolus infusions of crystalloids on serum albumin, haematocrit, serum and urinary biochemistry and bioelectrical impedance analysis were measured in healthy subjects. Ten male volunteers received 2-litre infusions of 0.9% [...]