HAZARDS OF ULTRA-MARATHON RUNNING IN THE SCOTTISH HIGHLANDS: EXERCISE-ASSOCIATED HYPONATRAEMIA

The case histories are presented of four athletes taking part in a 95-mile ultra-endurance foot race in Scotland who were hospitalised after developing exercise-associated hyponatraemia and rhabdomyolysis. Exercise-associated hyponatraemia is relatively uncommon in temperate climates. Risk factors disposing to this disorder are discussed. Exercise-associated hyponatraemia is thought to be due to overconsumption of hypotonic fluid [...]

ORAL REHYDRATION SOLUTIONS IN NON-CHOLERA DIARRHEA: A REVIEW

The use of oral rehydration solution (ORS) has revolutionized the management of acute diarrhea. The implementation of the standard World Health Organization ORS (WHO-ORS) has resulted in decreased mortality associated with acute diarrheal illnesses in children, although in general stool volume and diarrhea durations are not reduced. Decreased morbidity and mortality have occurred because of [...]

THE HISTORY OF 0.9% SALINE

BACKGROUND & AIMS: We aimed to trace the historical origins of 0.9% saline, how it came to be used so commonly today, and to consider whether its continued use can be justified. METHODS: We searched the Medline, Science Citation Index, ScienceDirect and Google databases using the key words saline, physiological, salt solution, sodium chloride, 0.9%, [...]

THIRST AND FLUID REGULATORY RESPONSES TO HYPERTONICITY IN OLDER ADULTS

To assess the fluid regulatory responses in aging adults, we measured thirst perception and osmoregulation during and after infusion of hypertonic NaCl) saline in older (72 +/- 2 yr, n = 6) and younger (26 +/- n = 6) subjects. Hypertonic saline was infused at 0.1 min-1.kg-1 for 120 min. On a separate day, the [...]

By |2013-01-31T18:34:20+00:00enero 31st, 2013|Age and the elderly, Scientific papers|0 Comments

THE TREATMENT OF HYPONATREMIA

Virtually all investigators now agree that self-induced water intoxication, symptomatic hospital-acquired hyponatremia, and hyponatremia associated with intracranial pathology are true emergencies that demand prompt and definitive intervention with hypertonic saline. A 4- to 6-mmol/L increase in serum sodium concentration is adequate in the most seriously ill patients and this is best achieved with bolus infusions [...]

MECHANISM OF ATTENUATED THIRST IN AGING: ROLE OF CENTRAL VOLUME RECEPTORS

To test the hypothesis that the inhibitory action of central blood volume expansion on thirst and renal fluid regulation is attenuated with aging, we monitored the drinking and renal responses of dehydrated older (70 +/- 2 yr, n = 6) and younger (24 +/- 1 yr, n = 6) subjects during 195 min of head-out [...]

By |2013-01-31T18:34:20+00:00enero 31st, 2013|Age and the elderly, Scientific papers|0 Comments

THIRST AND HYDRATION: PHYSIOLOGY AND CONSEQUENCES OF DYSFUNCTION

The constant supply of oxygen and nutriments to cells (especially neurons) is the role of the cardiovascular system. The constant supply of water (and sodium) for cardiovascular function is the role of thirst and sodium appetite and kidney function. This physiological regulation ensures that plasma volume and osmolality are maintained within set limits by initiating [...]

By |2013-01-31T18:34:20+00:00enero 31st, 2013|Physical performance, Scientific papers|0 Comments

VARIATION OF SKIN SURFACE PH, SEBUM CONTENT AND STRATUM CORNEUM HYDRATION WITH AGE AND GENDER IN A LARGE CHINESE POPULATION.

BACKGROUND AND OBJECTIVES: Evidence suggests the importance of skin biophysical properties in predicting diseases and in developing appropriate skin care. The results to date of studies on skin surface pH, stratum corneum (SC) hydration and sebum content in both genders and at various ages have been inconclusive, which was in part due to small sample [...]

By |2013-01-31T18:34:20+00:00enero 31st, 2013|Age and the elderly, Scientific papers|0 Comments

TOTAL BODY WATER CHANGES AFTER AN EXERCISE INTERVENTION TRACKED USING BIOIMPEDANCE SPECTROSCOPY: A DEUTERIUM OXIDE COMPARISON

BACKGROUND & AIMS: Bioimpedance spectroscopy (BIS) for the estimation of total body water (TBW) has advantages over isotope dilution techniques, including cost, portability, and ease of use. The aim of the current study was to determine the validity of a BIS device (Imp SFB7) for tracking changes in overfat and obese individuals. METHODS: Sixty overfat [...]

By |2013-01-31T18:34:20+00:00enero 31st, 2013|Assessment methodologies, Scientific papers|0 Comments